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MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage

Aging is accompanied by altered intercellular communication, deregulated metabolic function, and inflammation. Interventions that restore a youthful state delay or reverse these processes, prompting the search for systemic regulators of metabolic and immune homeostasis. Here we identify MANF, a secr...

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Detalles Bibliográficos
Autores principales: Sousa-Victor, Pedro, Neves, Joana, Cedron-Craft, Wendy, Ventura, P. Britten, Liao, Chen-Yu, Riley, Rebeccah R., Soifer, Ilya, van Bruggen, Nicholas, Kolumam, Ganesh A., Villeda, Saul A., Lamba, Deepak A., Jasper, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727652/
https://www.ncbi.nlm.nih.gov/pubmed/31489403
http://dx.doi.org/10.1038/s42255-018-0023-6