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Ancient complement and lineage-specific evolution of the Sec7 ARF GEF proteins in eukaryotes
Guanine nucleotide exchange factors (GEFs) are the initiators of signaling by every regulatory GTPase, which in turn act to regulate a wide array of essential cellular processes. To date, each family of GTPases is activated by distinct families of GEFs. Bidirectional membrane trafficking is regulate...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727740/ https://www.ncbi.nlm.nih.gov/pubmed/31141460 http://dx.doi.org/10.1091/mbc.E19-01-0073 |