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Ancient complement and lineage-specific evolution of the Sec7 ARF GEF proteins in eukaryotes

Guanine nucleotide exchange factors (GEFs) are the initiators of signaling by every regulatory GTPase, which in turn act to regulate a wide array of essential cellular processes. To date, each family of GTPases is activated by distinct families of GEFs. Bidirectional membrane trafficking is regulate...

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Detalles Bibliográficos
Autores principales: Pipaliya, Shweta V., Schlacht, Alexander, Klinger, Christen M., Kahn, Richard A., Dacks, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727740/
https://www.ncbi.nlm.nih.gov/pubmed/31141460
http://dx.doi.org/10.1091/mbc.E19-01-0073

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