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AKAP79/150 recruits the transcription factor NFAT to regulate signaling to the nucleus by neuronal L-type Ca(2+) channels

In neurons, regulation of activity-dependent transcription by the nuclear factor of activated T-cells (NFAT) depends upon Ca(2+) influx through voltage-gated L-type calcium channels (LTCC) and NFAT translocation to the nucleus following its dephosphorylation by the Ca(2+)-dependent phosphatase calci...

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Detalles Bibliográficos
Autores principales: Murphy, Jonathan G., Crosby, Kevin C., Dittmer, Philip J., Sather, William A., Dell’Acqua, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727748/
https://www.ncbi.nlm.nih.gov/pubmed/31091162
http://dx.doi.org/10.1091/mbc.E19-01-0060