Clathrin and clathrin adaptor AP-1 control apical trafficking of megalin in the biosynthetic and recycling routes

Megalin (gp330, LRP-2) is a protein structurally related to the low-density lipoprotein receptor family that displays a large luminal domain with multiligand binding properties. Megalin localizes to the apical surface of multiple epithelia, where it participates in endocytosis of a variety of ligand...

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Detalles Bibliográficos
Autores principales: Gravotta, Diego, Perez Bay, Andres, Jonker, Caspar T. H., Zager, Patrick J., Benedicto, Ignacio, Schreiner, Ryan, Caceres, Paulo S., Rodriguez-Boulan, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727755/
https://www.ncbi.nlm.nih.gov/pubmed/31091172
http://dx.doi.org/10.1091/mbc.E18-12-0811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727755/
https://www.ncbi.nlm.nih.gov/pubmed/31091172
http://dx.doi.org/10.1091/mbc.E18-12-0811

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