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Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast

Dividing cells must balance the maintenance of genome integrity with the generation of cytoskeletal forces that control chromosome position. In this study, we investigate how forces on astral microtubules impact the genome during cell division by using live-cell imaging of the cytoskeleton, chromati...

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Detalles Bibliográficos
Autores principales: Estrem, Cassi, Moore, Jeffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727761/
https://www.ncbi.nlm.nih.gov/pubmed/31067146
http://dx.doi.org/10.1091/mbc.E18-12-0808