Association of Germline Variants in Natural Killer Cells With Tumor Immune Microenvironment Subtypes, Tumor-Infiltrating Lymphocytes, Immunotherapy Response, Clinical Outcomes, and Cancer Risk

IMPORTANCE: Only a small fraction of patients with cancer receiving immune checkpoint therapy (ICT) respond, which is associated with tumor immune microenvironment (TIME) subtypes and tumor-infiltrating lymphocytes (TILs). OBJECTIVE: To examine whether germline variants of natural killer (NK) cells,...

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Detalles Bibliográficos
Autores principales: Xu, Xue, Li, Jianqiang, Zou, Jinfeng, Feng, Xiaowen, Zhang, Chao, Zheng, Ruiqing, Duanmu, Weixiang, Saha-Mandal, Arnab, Ming, Zhong, Wang, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727785/
https://www.ncbi.nlm.nih.gov/pubmed/31483464
http://dx.doi.org/10.1001/jamanetworkopen.2019.9292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727785/
https://www.ncbi.nlm.nih.gov/pubmed/31483464
http://dx.doi.org/10.1001/jamanetworkopen.2019.9292

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