Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the rDNA of Saccharomyces cerevisiae

The complex structure and repetitive nature of eukaryotic ribosomal DNA (rDNA) is a challenge for genome assembly, thus the consequences of sequence variation in rDNA remain unexplored. However, renewed interest in the role that rDNA variation may play in diverse cellular functions, aside from ribos...

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Detalles Bibliográficos
Autores principales: Sanchez, Joseph C., Ollodart, Anja, Large, Christopher R. L., Clough, Courtnee, Alvino, Gina M., Tsuchiya, Mitsuhiro, Crane, Matthew, Kwan, Elizabeth X., Kaeberlein, Matt, Dunham, Maitreya J., Raghuraman, M. K., Brewer, Bonita J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727806/
https://www.ncbi.nlm.nih.gov/pubmed/31292210
http://dx.doi.org/10.1534/genetics.119.302351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727806/
https://www.ncbi.nlm.nih.gov/pubmed/31292210
http://dx.doi.org/10.1534/genetics.119.302351

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