A Unique SUMO-Interacting Motif of Trx2 Is Critical for Its Mitochondrial Presequence Processing and Anti-oxidant Activity

OBJECTIVE: Mitochondrial thioredoxin 2 (Trx2) is a vital mitochondrial redox protein that mediates normal protein thiol reduction and provides electrons to peroxiredoxin 3 (Prx3) to scavenge H(2)O(2) in mitochondria. It has been widely reported that Trx2 deletion in cells or mice generates massive r...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chaofei, Wang, Kang, Zhang, Haifeng, Zhou, Huanjiao Jenny, Chen, Yuxin, Min, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727865/
https://www.ncbi.nlm.nih.gov/pubmed/31555141
http://dx.doi.org/10.3389/fphys.2019.01089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727865/
https://www.ncbi.nlm.nih.gov/pubmed/31555141
http://dx.doi.org/10.3389/fphys.2019.01089

Ejemplares similares