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A spray freeze dried micropellet based formulation proof-of-concept for a yellow fever vaccine candidate
The stability of live-attenuated viruses is very challenging due to thermal sensitivity; therefore, solid form is usually required (often freeze-dried products). Micropellet technology is a lyophilization technology that has the potential to provide greater flexibility in the presentation of a given...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727866/ https://www.ncbi.nlm.nih.gov/pubmed/31306751 http://dx.doi.org/10.1016/j.ejpb.2019.07.008 |