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A spray freeze dried micropellet based formulation proof-of-concept for a yellow fever vaccine candidate

The stability of live-attenuated viruses is very challenging due to thermal sensitivity; therefore, solid form is usually required (often freeze-dried products). Micropellet technology is a lyophilization technology that has the potential to provide greater flexibility in the presentation of a given...

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Detalles Bibliográficos
Autores principales: Clénet, Didier, Hourquet, Véronique, Woinet, Bertrand, Ponceblanc, Hervé, Vangelisti, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727866/
https://www.ncbi.nlm.nih.gov/pubmed/31306751
http://dx.doi.org/10.1016/j.ejpb.2019.07.008