Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice

B6.Nba2 mice spontaneously develop a lupus-like disease characterized by elevated levels of serum anti-nuclear autoantibody (ANA) immune complexes and constitutive type I interferon (IFNα) production. During disease progression, both plasmacytoid dendritic cells (pDCs) and antibody secreting plasma...

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Detalles Bibliográficos
Autores principales: Davison, Laura M., Liu, Jessica C., Huang, Lei, Carroll, Thomas M., Mellor, Andrew L., Jørgensen, Trine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727869/
https://www.ncbi.nlm.nih.gov/pubmed/31555267
http://dx.doi.org/10.3389/fimmu.2019.02017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727869/
https://www.ncbi.nlm.nih.gov/pubmed/31555267
http://dx.doi.org/10.3389/fimmu.2019.02017

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