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A systems biology approach towards the identification of candidate therapeutic genes and potential biomarkers for Parkinson’s disease

Parkinson’s disease (PD) is an irreversible and incurable multigenic neurodegenerative disorder. It involves progressive loss of mid brain dopaminergic neurons in the substantia nigra pars compacta (SN). We compared brain gene expression profiles with those from the peripheral blood cells of a separ...

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Detalles Bibliográficos
Autores principales: Sakharkar, Meena Kishore, Kashmir Singh, Sarinder Kaur, Rajamanickam, Karthic, Mohamed Essa, Musthafa, Yang, Jian, Chidambaram, Saravana Babu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728017/
https://www.ncbi.nlm.nih.gov/pubmed/31487305
http://dx.doi.org/10.1371/journal.pone.0220995