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Deep generative models for T cell receptor protein sequences

Probabilistic models of adaptive immune repertoire sequence distributions can be used to infer the expansion of immune cells in response to stimulus, differentiate genetic from environmental factors that determine repertoire sharing, and evaluate the suitability of various target immune sequences fo...

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Detalles Bibliográficos
Autores principales: Davidsen, Kristian, Olson, Branden J, DeWitt, William S, Feng, Jean, Harkins, Elias, Bradley, Philip, Matsen, Frederick A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728137/
https://www.ncbi.nlm.nih.gov/pubmed/31487240
http://dx.doi.org/10.7554/eLife.46935