Amyloid-β Oligomers Regulate ADAM10 Synaptic Localization Through Aberrant Plasticity Phenomena

A disintegrin and metalloproteinase 10 (ADAM10) is a synaptic enzyme that has been previously shown to limit amyloid-β(1–42) (Aβ(1–42)) peptide formation in Alzheimer’s disease (AD). Furthermore, ADAM10 participates to spine shaping through the cleavage of adhesion molecules and its activity is unde...

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Detalles Bibliográficos
Autores principales: Marcello, Elena, Musardo, Stefano, Vandermeulen, Lina, Pelucchi, Silvia, Gardoni, Fabrizio, Santo, Nadia, Antonucci, Flavia, Di Luca, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728288/
https://www.ncbi.nlm.nih.gov/pubmed/30989630
http://dx.doi.org/10.1007/s12035-019-1583-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728288/
https://www.ncbi.nlm.nih.gov/pubmed/30989630
http://dx.doi.org/10.1007/s12035-019-1583-5

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