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ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1

N(6)-Methyladenosine (m(6)A) is the most common posttranscriptional modification of RNA and plays critical roles in cancer pathogenesis. However, the biological function of long noncoding RNA (lncRNA) methylation remains unclear. As a demethylase, ALKBH5 (alkylation repair homolog protein 5) is invo...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Guo, Shuai, Piao, Hai-yan, Wang, Yue, Wu, Yue, Meng, Xiang-yu, Yang, Dong, Zheng, Zhi-chao, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728298/
https://www.ncbi.nlm.nih.gov/pubmed/31290116
http://dx.doi.org/10.1007/s13105-019-00690-8