Cargando…

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication

Most current evidence indicates that DNA polymerases ε and δ, respectively, perform the bulk of leading and lagging strand replication of the eukaryotic nuclear genome. Given that ribonucleotide and mismatch incorporation rates by these replicases influence somatic and germline patterns of variation...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Zhi-Xiong, Lujan, Scott A., Burkholder, Adam B., Garbacz, Marta A., Kunkel, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728351/
https://www.ncbi.nlm.nih.gov/pubmed/31488849
http://dx.doi.org/10.1038/s41467-019-11995-z