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Crystal structure and chemical inhibition of essential schistosome host-interactive virulence factor carbonic anhydrase SmCA
The intravascular parasitic worm Schistosoma mansoni is a causative agent of schistosomiasis, a disease of great global public health significance. Here we identify an α-carbonic anhydrase (SmCA) that is expressed at the schistosome surface as determined by activity assays and immunofluorescence/imm...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728359/ https://www.ncbi.nlm.nih.gov/pubmed/31508507 http://dx.doi.org/10.1038/s42003-019-0578-0 |