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Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening

Lung cancer shows substantial genetic and phenotypic heterogeneity across individuals, driving a need for personalised medicine. Here, we report lung cancer organoids and normal bronchial organoids established from patient tissues comprising five histological subtypes of lung cancer and non-neoplast...

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Detalles Bibliográficos
Autores principales: Kim, Minsuh, Mun, Hyemin, Sung, Chang Oak, Cho, Eun Jeong, Jeon, Hye-Joon, Chun, Sung-Min, Jung, Da Jung, Shin, Tae Hoon, Jeong, Gi Seok, Kim, Dong Kwan, Choi, Eun Kyung, Jeong, Seong-Yun, Taylor, Alison M., Jain, Sejal, Meyerson, Matthew, Jang, Se Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728380/
https://www.ncbi.nlm.nih.gov/pubmed/31488816
http://dx.doi.org/10.1038/s41467-019-11867-6