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Sex-specific Mendelian randomization study of genetically predicted insulin and cardiovascular events in the UK Biobank
Insulin drives growth and reproduction which trade-off against longevity. Genetically predicted insulin, i.e., insulin proxied by genetic variants, is positively associated with ischemic heart disease, but sex differences are unclear, despite different disease rates and reproductive strategies by se...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728387/ https://www.ncbi.nlm.nih.gov/pubmed/31508506 http://dx.doi.org/10.1038/s42003-019-0579-z |