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Actin Cytoskeletal Reorganization Function of JRAB/MICAL-L2 Is Fine-tuned by Intramolecular Interaction between First LIM Zinc Finger and C-terminal Coiled-coil Domains

JRAB/MICAL-L2 is an effector protein of Rab13, a member of the Rab family of small GTPase. JRAB/MICAL-L2 consists of a calponin homology domain, a LIM domain, and a coiled-coil domain. JRAB/MICAL-L2 engages in intramolecular interaction between the N-terminal LIM domain and the C-terminal coiled-coi...

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Detalles Bibliográficos
Autores principales: Miyake, Kazuhisa, Sakane, Ayuko, Tsuchiya, Yuko, Sagawa, Ikuko, Tomida, Yoko, Kasahara, Jiro, Imoto, Issei, Watanabe, Shio, Higo, Daisuke, Mizuguchi, Kenji, Sasaki, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728388/
https://www.ncbi.nlm.nih.gov/pubmed/31488862
http://dx.doi.org/10.1038/s41598-019-49232-8