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Inhibition of phosphatidylinositol 3‐kinase α (PI3Kα) prevents heterotopic ossification
Heterotopic ossification (HO) is the pathological formation of ectopic endochondral bone within soft tissues. HO occurs following mechanical trauma, burns, or congenitally in patients suffering from fibrodysplasia ossificans progressiva (FOP). FOP patients carry a conserved mutation in ACVR1 that be...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728602/ https://www.ncbi.nlm.nih.gov/pubmed/31373426 http://dx.doi.org/10.15252/emmm.201910567 |