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From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs

Reversing or slowing the aging process brings great promise to treat or prevent age‐related disease, and targeting the hallmarks of aging is a strategy to achieve this. Epigenetics affects several if not all of the hallmarks of aging and has therefore emerged as a central target for intervention. On...

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Detalles Bibliográficos
Autores principales: McIntyre, Rebecca L, Daniels, Eileen G, Molenaars, Marte, Houtkooper, Riekelt H, Janssens, Georges E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728603/
https://www.ncbi.nlm.nih.gov/pubmed/31368626
http://dx.doi.org/10.15252/emmm.201809854