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Trastuzumab-Coated Nanoparticles Loaded With Docetaxel for Breast Cancer Therapy

Docetaxel (DTX) is commonly used for breast cancer treatment. Tween 80 used for DTX dissolution in its clinical formulation causes severe hypersensitivity and other adverse reactions. In this study, trastuzumab (Tmab)-coated lipid-polymer hybrid nanoparticles (PLNs) were prepared, composed of poly (...

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Detalles Bibliográficos
Autores principales: Zhang, Xueyan, Liu, Jiaxin, Li, Xiangyu, Li, Fang, Lee, Robert J., Sun, Fengying, Li, Youxin, Liu, Zongyu, Teng, Lesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728688/
https://www.ncbi.nlm.nih.gov/pubmed/31523204
http://dx.doi.org/10.1177/1559325819872583