Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor

Inhibition of histone deacetylases (HDACs) has been an important emerging therapy for the treatment of multiple cancers. However, the application of HDAC inhibitors is restricted by the limited potency against solid tumors. In order to discover novel HDAC inhibitors with potent antitumor activities,...

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Detalles Bibliográficos
Autores principales: Zhang, Lihui, Li, Xiaoyang, Chen, Yiming, Wan, Minghui, Jiang, Qixiao, Zhang, Li, Chou, C. James, Song, Weiguo, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730478/
https://www.ncbi.nlm.nih.gov/pubmed/31543818
http://dx.doi.org/10.3389/fphar.2019.00957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730478/
https://www.ncbi.nlm.nih.gov/pubmed/31543818
http://dx.doi.org/10.3389/fphar.2019.00957

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