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Macrophages From Subjects With Isolated GH/IGF-I Deficiency Due to a GHRH Receptor Gene Mutation Are Less Prone to Infection by Leishmania amazonensis

Isolated growth hormone (GH) deficiency (IGHD) affects approximately 1 in 4,000 to 1 in 10,000 individuals worldwide. We have previously described a large cohort of subjects with IGHD due to a homozygous mutation in the GH releasing hormone (GHRH) receptor gene. These subjects exhibit throughout the...

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Detalles Bibliográficos
Autores principales: Barrios, Mônica R., Campos, Viviane C., Peres, Nalu T. A., de Oliveira, Laís L., Cazzaniga, Rodrigo A., Santos, Márcio B., Aires, Murilo B., Silva, Ricardo L. L., Barreto, Aline, Goto, Hiro, Almeida, Roque P., Salvatori, Roberto, Aguiar-Oliveira, Manuel H., Jesus, Amélia M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730494/
https://www.ncbi.nlm.nih.gov/pubmed/31544067
http://dx.doi.org/10.3389/fcimb.2019.00311