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KRAS-Driven Metabolic Rewiring Reveals Novel Actionable Targets in Cancer
Tumors driven by mutant KRAS are among the most aggressive and refractory to treatment. Unfortunately, despite the efforts, targeting alterations of this GTPase, either directly or by acting on the downstream signaling cascades, has been, so far, largely unsuccessful. However, recently, novel therap...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730590/ https://www.ncbi.nlm.nih.gov/pubmed/31544066 http://dx.doi.org/10.3389/fonc.2019.00848 |