Mechanistic studies on the absorption enhancement of a self-nanoemulsifying drug delivery system loaded with norisoboldine-phospholipid complex

BACKGROUND: Norisoboldine (NOR), the main isoquinoline alkaloid constituent in Radix Linderae, was demonstrated to have an outstanding anti-arthritis activity. However, a poor oral bioavailability of NOR creates a barrier for its development and application. METHODS: A new self-nanoemulsifying drug...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Wen, Xiaoxia, Dai, Yue, Xia, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730610/
https://www.ncbi.nlm.nih.gov/pubmed/31564867
http://dx.doi.org/10.2147/IJN.S211905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730610/
https://www.ncbi.nlm.nih.gov/pubmed/31564867
http://dx.doi.org/10.2147/IJN.S211905

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