Cargando…

A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes

Antibodies are essential to functional immunity, yet the epitopes targeted by antibody repertoires remain largely uncharacterized. To aid in characterization, we developed a generalizable strategy to predict antibody-binding epitopes within individual proteins and entire proteomes. Specifically, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Paull, Michael L., Johnston, Tim, Ibsen, Kelly N., Bozekowski, Joel D., Daugherty, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730857/
https://www.ncbi.nlm.nih.gov/pubmed/31490930
http://dx.doi.org/10.1371/journal.pone.0217668