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A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes
Antibodies are essential to functional immunity, yet the epitopes targeted by antibody repertoires remain largely uncharacterized. To aid in characterization, we developed a generalizable strategy to predict antibody-binding epitopes within individual proteins and entire proteomes. Specifically, we...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730857/ https://www.ncbi.nlm.nih.gov/pubmed/31490930 http://dx.doi.org/10.1371/journal.pone.0217668 |