Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms

Elevated expression of the iron regulatory protein, ferritin heavy chain 1 (FTH1), is increasingly being associated with high tumor grade and poor survival outcomes in glioblastoma. Glioma initiating cells (GICs), a small population of stem-like cells implicated in therapeutic resistance and gliobla...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravi, Vagisha, Madhankumar, Achuthamangalam B., Abraham, Thomas, Slagle-Webb, Becky, Connor, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730865/
https://www.ncbi.nlm.nih.gov/pubmed/31491006
http://dx.doi.org/10.1371/journal.pone.0221952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730865/
https://www.ncbi.nlm.nih.gov/pubmed/31491006
http://dx.doi.org/10.1371/journal.pone.0221952

Ejemplares similares