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Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms

Elevated expression of the iron regulatory protein, ferritin heavy chain 1 (FTH1), is increasingly being associated with high tumor grade and poor survival outcomes in glioblastoma. Glioma initiating cells (GICs), a small population of stem-like cells implicated in therapeutic resistance and gliobla...

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Detalles Bibliográficos
Autores principales:	Ravi, Vagisha, Madhankumar, Achuthamangalam B., Abraham, Thomas, Slagle-Webb, Becky, Connor, James R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730865/ https://www.ncbi.nlm.nih.gov/pubmed/31491006 http://dx.doi.org/10.1371/journal.pone.0221952

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