Tamoxifen suppresses pancreatic β-cell proliferation in mice

Tamoxifen is a mixed agonist/antagonist estrogen analogue that is frequently used to induce conditional gene deletion in mice using Cre-loxP mediated gene recombination. Tamoxifen is routinely employed in extremely high-doses relative to typical human doses to induce efficient gene deletion in mice....

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Surl-Hee, Granger, Anne, Rankin, Matthew M., Lam, Carol J., Cox, Aaron R., Kushner, Jake A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731016/
https://www.ncbi.nlm.nih.gov/pubmed/31490929
http://dx.doi.org/10.1371/journal.pone.0214829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731016/
https://www.ncbi.nlm.nih.gov/pubmed/31490929
http://dx.doi.org/10.1371/journal.pone.0214829

Ejemplares similares