Dengue genetic divergence generates within-serotype antigenic variation, but serotypes dominate evolutionary dynamics

Dengue virus (DENV) exists as four genetically distinct serotypes, each of which is historically assumed to be antigenically uniform. Recent analyses suggest that antigenic heterogeneity may exist within each serotype, but its source, extent and impact remain unclear. Here, we construct a sequence-b...

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Detalles Bibliográficos
Autores principales: Bell, Sidney M, Katzelnick, Leah, Bedford, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731059/
https://www.ncbi.nlm.nih.gov/pubmed/31385805
http://dx.doi.org/10.7554/eLife.42496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731059/
https://www.ncbi.nlm.nih.gov/pubmed/31385805
http://dx.doi.org/10.7554/eLife.42496

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