Cargando…

Regulation of Eag1 gating by its intracellular domains

Voltage-gated potassium channels (K(v)s) are gated by transmembrane voltage sensors (VS) that move in response to changes in membrane voltage. K(v)10.1 or Eag1 also has three intracellular domains: PAS, C-linker, and CNBHD. We demonstrate that the Eag1 intracellular domains are not required for volt...

Descripción completa

Detalles Bibliográficos
Autores principales: Whicher, Jonathan R, MacKinnon, Roderick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731095/
https://www.ncbi.nlm.nih.gov/pubmed/31490124
http://dx.doi.org/10.7554/eLife.49188