A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation

There is a need for preclinical models that can enable identification of novel radiosensitizing drugs in clinically relevant high-throughput experiments. We used a new high-throughput compatible total cell kill spheroid assay to study the interaction between drugs and radiation in order to identify...

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Detalles Bibliográficos
Autores principales: Karlsson, Henning, Senkowski, Wojciech, Fryknäs, Mårten, Mansoori, Sharmineh, Linder, Stig, Gullbo, Joachim, Larsson, Rolf, Nygren, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731106/
https://www.ncbi.nlm.nih.gov/pubmed/31523395
http://dx.doi.org/10.18632/oncotarget.27166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731106/
https://www.ncbi.nlm.nih.gov/pubmed/31523395
http://dx.doi.org/10.18632/oncotarget.27166

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