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A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation
There is a need for preclinical models that can enable identification of novel radiosensitizing drugs in clinically relevant high-throughput experiments. We used a new high-throughput compatible total cell kill spheroid assay to study the interaction between drugs and radiation in order to identify...
Autores principales: | Karlsson, Henning, Senkowski, Wojciech, Fryknäs, Mårten, Mansoori, Sharmineh, Linder, Stig, Gullbo, Joachim, Larsson, Rolf, Nygren, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731106/ https://www.ncbi.nlm.nih.gov/pubmed/31523395 http://dx.doi.org/10.18632/oncotarget.27166 |
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