Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers

BACKGROUND AND PURPOSE: The objective of this study was to longitudinally investigate the trajectory of change in (1)H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow‐up, and to determine the time at which the neurochemical alterations accelerated during...

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Detalles Bibliográficos
Autores principales: Chen, Qin, Boeve, Bradley F., Tosakulwong, Nirubol, Lesnick, Timothy, Brushaber, Danielle, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Haley, Dana, Gunter, Jeffrey L., Graff‐Radford, Jonathan, Jones, David, Knopman, David, Graff‐Radford, Neill, Kraft, Ruth, Lapid, Maria, Rademakers, Rosa, Wszolek, Zbigniew K., Rosen, Howie, Boxer, Adam L., Kantarci, Kejal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731148/
https://www.ncbi.nlm.nih.gov/pubmed/31173437
http://dx.doi.org/10.1111/jon.12642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731148/
https://www.ncbi.nlm.nih.gov/pubmed/31173437
http://dx.doi.org/10.1111/jon.12642

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