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The effect of mid-life insulin resistance and type 2 diabetes on older-age cognitive state: the explanatory role of early-life advantage

AIMS/HYPOTHESIS: Type 2 diabetes, hyperglycaemia and insulin resistance are associated with cognitive impairment and dementia, but causal inference studies using Mendelian randomisation do not confirm this. We hypothesised that early-life cognition and social/educational advantage may confound the r...

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Detalles Bibliográficos
Autores principales: James, Sarah-Naomi, Wong, Andrew, Tillin, Therese, Hardy, Rebecca, Chaturvedi, Nishi, Richards, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731197/
https://www.ncbi.nlm.nih.gov/pubmed/31359084
http://dx.doi.org/10.1007/s00125-019-4949-3