Drug repurposing for Alzheimer’s disease based on transcriptional profiling of human iPSC-derived cortical neurons

Alzheimer’s disease is a complex disorder encompassing multiple pathological features with associated genetic and molecular culprits. However, target-based therapeutic strategies have so far proved ineffective. The aim of this study is to develop a methodology harnessing the transcriptional changes...

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Detalles Bibliográficos
Autores principales: Williams, Gareth, Gatt, Ariana, Clarke, Earl, Corcoran, Jonathan, Doherty, Patrick, Chambers, David, Ballard, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731247/
https://www.ncbi.nlm.nih.gov/pubmed/31492831
http://dx.doi.org/10.1038/s41398-019-0555-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731247/
https://www.ncbi.nlm.nih.gov/pubmed/31492831
http://dx.doi.org/10.1038/s41398-019-0555-x

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