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Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery
An early bottleneck in the rapid isolation of new antibody fragment binders using in vitro library approaches is the inertia encountered in acquiring and preparing soluble antigen fragments. In this report, we describe a simple, yet powerful strategy that exploits the properties of the SpyCatcher/Sp...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731262/ https://www.ncbi.nlm.nih.gov/pubmed/31492910 http://dx.doi.org/10.1038/s41598-019-49233-7 |