Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

Population-based biobanks with genomic and dense phenotype data provide opportunities for generating effective therapeutic hypotheses and understanding the genomic role in disease predisposition. To characterize latent components of genetic associations, we apply truncated singular value decompositi...

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Detalles Bibliográficos
Autores principales: Tanigawa, Yosuke, Li, Jiehan, Justesen, Johanne M., Horn, Heiko, Aguirre, Matthew, DeBoever, Christopher, Chang, Chris, Narasimhan, Balasubramanian, Lage, Kasper, Hastie, Trevor, Park, Chong Y., Bejerano, Gill, Ingelsson, Erik, Rivas, Manuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731283/
https://www.ncbi.nlm.nih.gov/pubmed/31492854
http://dx.doi.org/10.1038/s41467-019-11953-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731283/
https://www.ncbi.nlm.nih.gov/pubmed/31492854
http://dx.doi.org/10.1038/s41467-019-11953-9

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