Corticosteroid eye drop instillation aggravates the development of Acanthamoeba keratitis in rabbit corneas inoculated with Acanthamoeba and bacteria

The role of topical corticosteroids in management of Acanthamoeba keratitis (AK) remains controversial. Using a rabbit AK model, we investigated whether corticosteroid use is a risk factor of AK. Acanthamoeba (1 × 10(5)/ml) was incubated with two densities of P. aeruginosa (PA; high-PA: 1 × 10(8)/ml...

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Detalles Bibliográficos
Autores principales: Nakagawa, Hayate, Koike, Naohito, Ehara, Tomoko, Hattori, Takaaki, Narimatsu, Akitomo, Kumakura, Shigeto, Goto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731293/
https://www.ncbi.nlm.nih.gov/pubmed/31492880
http://dx.doi.org/10.1038/s41598-019-49128-7

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