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Phlda3 regulates beta cell survival during stress

The loss of functional beta cell mass characterises all forms of diabetes. Beta cells are highly susceptible to stress, including cytokine, endoplasmic reticulum (ER) and oxidative stress. This study examined the role of pleckstrin homology-like, domain family A, member 3 (Phlda3) in beta cell survi...

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Detalles Bibliográficos
Autores principales: Bensellam, Mohammed, Chan, Jeng Yie, Lee, Kailun, Joglekar, Mugdha V., Hardikar, Anandwardhan A., Loudovaris, Thomas, Thomas, Helen E., Jonas, Jean-Christophe, Laybutt, D. Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731300/
https://www.ncbi.nlm.nih.gov/pubmed/31492921
http://dx.doi.org/10.1038/s41598-019-49289-5