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Phlda3 regulates beta cell survival during stress
The loss of functional beta cell mass characterises all forms of diabetes. Beta cells are highly susceptible to stress, including cytokine, endoplasmic reticulum (ER) and oxidative stress. This study examined the role of pleckstrin homology-like, domain family A, member 3 (Phlda3) in beta cell survi...
Autores principales: | Bensellam, Mohammed, Chan, Jeng Yie, Lee, Kailun, Joglekar, Mugdha V., Hardikar, Anandwardhan A., Loudovaris, Thomas, Thomas, Helen E., Jonas, Jean-Christophe, Laybutt, D. Ross |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731300/ https://www.ncbi.nlm.nih.gov/pubmed/31492921 http://dx.doi.org/10.1038/s41598-019-49289-5 |
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