Functional disease architectures reveal unique biological role of transposable elements

Transposable elements (TE) comprise roughly half of the human genome. Though initially derided as junk DNA, they have been widely hypothesized to contribute to the evolution of gene regulation. However, the contribution of TE to the genetic architecture of diseases remains unknown. Here, we analyze...

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Detalles Bibliográficos
Autores principales: Hormozdiari, Farhad, van de Geijn, Bryce, Nasser, Joseph, Weissbrod, Omer, Gazal, Steven, Ju, Chelsea J. -T., Connor, Luke O’, Hujoel, Margaux L. A., Engreitz, Jesse, Hormozdiari, Fereydoun, Price, Alkes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731302/
https://www.ncbi.nlm.nih.gov/pubmed/31492842
http://dx.doi.org/10.1038/s41467-019-11957-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731302/
https://www.ncbi.nlm.nih.gov/pubmed/31492842
http://dx.doi.org/10.1038/s41467-019-11957-5

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