SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair

Tissue injury induces changes in cellular identity, but the underlying molecular mechanisms remain obscure. Here, we show that upon damage in a mouse model, epidermal cells at the wound edge convert to an embryonic-like state, altering particularly the cytoskeletal/extracellular matrix (ECM) compone...

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Detalles Bibliográficos
Autores principales: Miao, Qi, Hill, Matthew C., Chen, Fengju, Mo, Qianxing, Ku, Amy T., Ramos, Carlos, Sock, Elisabeth, Lefebvre, Véronique, Nguyen, Hoang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731344/
https://www.ncbi.nlm.nih.gov/pubmed/31492871
http://dx.doi.org/10.1038/s41467-019-11880-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731344/
https://www.ncbi.nlm.nih.gov/pubmed/31492871
http://dx.doi.org/10.1038/s41467-019-11880-9

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