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Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype
Rheumatoid arthritis (RA) is the most common immune-mediated arthritis. Anti-citrullinated peptide antibodies (ACPA) are highly specific to RA and assayed with the commercial CCP2 assay. Genetic drivers of RA within the MHC are different for CCP2-positive and -negative subsets of RA, particularly at...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731376/ https://www.ncbi.nlm.nih.gov/pubmed/31474319 http://dx.doi.org/10.1016/j.ajhg.2019.08.002 |