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Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells
Premature senescence, a death escaping pathway for cells experiencing stress, is conducive to aging and cardiovascular diseases. The molecular switch between senescent and apoptotic fate remains, however, poorly recognized. Nrf2 is an important transcription factor orchestrating adaptive response to...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731384/ https://www.ncbi.nlm.nih.gov/pubmed/31491600 http://dx.doi.org/10.1016/j.redox.2019.101304 |