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Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells

Premature senescence, a death escaping pathway for cells experiencing stress, is conducive to aging and cardiovascular diseases. The molecular switch between senescent and apoptotic fate remains, however, poorly recognized. Nrf2 is an important transcription factor orchestrating adaptive response to...

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Detalles Bibliográficos
Autores principales: Kopacz, Aleksandra, Klóska, Damian, Proniewski, Bartosz, Cysewski, Dominik, Personnic, Nicolas, Piechota-Polańczyk, Aleksandra, Kaczara, Patrycja, Zakrzewska, Agnieszka, Forman, Henry Jay, Dulak, Józef, Józkowicz, Alicja, Grochot-Przęczek, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731384/
https://www.ncbi.nlm.nih.gov/pubmed/31491600
http://dx.doi.org/10.1016/j.redox.2019.101304