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Malignant Glioma Therapy by Vaccination with Irradiated C6 Cell-Derived Microvesicles Promotes an Antitumoral Immune Response

Glioblastoma is the most common and malignant tumor of the CNS, with a mean survival of 14 months after diagnosis. Its unfavorable prognosis reveals the need for novel therapies. It is known that radiation can induce a systemic antitumor effect. Tumor cells produce and release microvesicles in respo...

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Detalles Bibliográficos
Autores principales: Pineda, Benjamín, Sánchez García, Francisco Javier, Olascoaga, Nora Karen, Pérez de la Cruz, Verónica, Salazar, Alelí, Moreno-Jiménez, Sergio, Hernández Pedro, Norma, Márquez-Navarro, Adrián, Ortiz Plata, Alma, Sotelo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731467/
https://www.ncbi.nlm.nih.gov/pubmed/31204210
http://dx.doi.org/10.1016/j.ymthe.2019.05.016