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OLIG2 is a novel immunohistochemical marker associated with the presence of PAX3/7-FOXO1 translocation in rhabdomyosarcomas

BACKGROUND: The most frequent histological types of rhabdomyosarcoma (RMS) in children are embryonal (ERMS) and alveolar (ARMS) tumours. The majority of ARMS are characterized by the presence of PAX3/7-FOXO1 gene fusion and have a worse prognosis than fusion gene-negative ARMS. However, identificati...

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Detalles Bibliográficos
Autores principales: Kaleta, Magdalena, Wakulińska, Anna, Karkucińska-Więckowska, Agnieszka, Dembowska-Bagińska, Bożenna, Grajkowska, Wiesława, Pronicki, Maciej, Łastowska, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731563/
https://www.ncbi.nlm.nih.gov/pubmed/31493794
http://dx.doi.org/10.1186/s13000-019-0883-4