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4.1B suppresses cancer cell proliferation by binding to EGFR P13 region of intracellular juxtamembrane segment

BACKGROUND: Gastric cancer (GC) has high incidence and mortality worldwide. However, the underlying mechanisms that regulate gastric carcinogenesis are largely undefined. 4.1B is an adaptor protein found at the interface of membrane and the cytoskeleton. Previous studies demonstrated that 4.1B serve...

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Detalles Bibliográficos
Autores principales: Xue, Fumin, An, Chao, Chen, Lixiang, Liu, Gang, Ren, Feifei, Guo, Xinhua, Sun, Haibin, Mei, Lu, Sun, Xiangdong, Li, Jinpeng, Tang, Youcai, An, Xiuli, Zheng, Pengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731589/
https://www.ncbi.nlm.nih.gov/pubmed/31492173
http://dx.doi.org/10.1186/s12964-019-0431-6